Now showing items 1-10 of 33
Genetics and genomics in Peru: Clinical and research perspective
(Wiley Open Access, 2018-12-25)
Peruvians currently preserve in their DNA the history of 2.5 million years of human evolution and 150,000 years of migration from Africa to Peru or the Americas. The development of Genetics and Genomics in the clinical and ...
Peruvian horse sickness virus and Yunnan orbivirus, isolated from vertebrates and mosquitoes in Peru and Australia
(Elsevier B.V., 2009-11-25)
During 1997, two new viruses were isolated from outbreaks of disease that occurred in horses, donkeys, cattle and sheep in Peru. Genome characterization showed that the virus isolated from horses (with neurological disorders, ...
A Novel Locus (RP24) for X-linked Retinitis Pigmentosa Maps to Xq26-27
(Cell Press, 1998-11)
Two genetic loci, RP2 and RP3, for X-linked retinitis pigmentosa (XLRP) have been localized to Xp11.3-11.23 and Xp21.1, respectively. RP3 appears to account for 70% of XLRP families; however, mutations in the RPGR gene ...
The current genomic landscape of western south america: andes, amazonia, and pacific coast.
(Society for Molecular Biology and Evolution, 2019-12)
Studies of Native South American genetic diversity have helped to shed light on the peopling and differentiation of the continent, but available data are sparse for the major ecogeographic domains. These include the Pacific ...
From colorectal cancer pattern to the characterization of individuals at risk: picture for genetic research in Latin America
(John Wiley & Sons Ltd, 2019-05-17)
Colorectal cancer (CRC) is one of the most common cancers in Latin America and the Caribbean, with the highest rates reported for Uruguay, Brazil and Argentina. We provide a global snapshot of the CRC patterns, how screening ...
Novel mutation in ENG gene causing Hereditary Hemorrhagic Telangiectasia in a Peruvian family
(Sociedade Brasileira de Genética, 2020)
Hereditary Hemorrhagic Telangiectasia (HHT) is a rare disorder of vascular development. Common manifestations include epistaxis, telangiectasias and arteriovenous malformations (AVMs) in multiple organs. Most patients have ...
Tracing the genomic ancestry of Peruvians reveals a major legacy of pre-Columbian ancestors
(Springer Nature Limited, 2013-07-18)
In order to investigate the underlying genetic structure and genomic ancestry proportions of Peruvian subpopulations, we analyzed 551 human samples of 25 localities from the Andean, Amazonian, and Coastal regions of Peru ...
Genetic ancestry of families of putative inka descent
(Springer-Verlag GmbH Alemania, 2018-03-03)
This study focuses on the descendants of the royal Inka family. The Inkas ruled Tawantinsuyu, the largest pre-Columbian empire in South America, which extended from southern Colombia to central Chile. The origin of the ...
A paleogenomic reconstruction of the deep population history of the andes
There are many unanswered questions about the population history of the Central and South Central Andes, particularly regarding the impact of large-scale societies, such as the Moche, Wari, Tiwanaku, and Inca. We assembled ...
Precision medicine for locally advanced breast cancer: frontiers and challenges in Latin America
(ECancer Medical Science, 2019-01-22)
Advances in high-throughput technologies and their involvement in the ‘omics’ of cancer have made possible the identification of hundreds of biomarkers and the development of predictive and prognostic platforms that model ...