Mostrando ítems 221-240 de 274

    • Precision medicine for locally advanced breast cancer: frontiers and challenges in Latin America 

      Pinto, Joseph A.; Saravia, César H.; Flores, Claudio; Araujo, Jhajaira M.; Martínez, David; Schwarz, Luis J.; Casas, Alberto; Bravo, Leny; Zavaleta, Jenny; Chuima, Brigitte; Alvarado, Hober; Fujita, Ricardo; Gómez, Henry L. (ECancer Medical Science, 2019-01-22)
      Acceso abierto
      Advances in high-throughput technologies and their involvement in the ‘omics’ of cancer have made possible the identification of hundreds of biomarkers and the development of predictive and prognostic platforms that model ...
    • Genetic identification of newborns in Peru: a pilot study 

      Neyra, Carlos D.; Suárez, Marilyn R.; Cueva, Eddie D.; Bailon, Henri; Gutiérrez, Ericson L. (Sociedad Chilena de Pediatría, 2019)
      Acceso abierto
      Objective: To determine the feasibility of genetic identification in a group of newborns from a public hospital in Lima, Peru. Material and Method: Descriptive cross-sectional study, carried out by the National Registry ...
    • Los asesores de tesis: ¿cumplen criterios de autoría? 

      Díaz-Vélez, Cristian; Fernández-Mogollón, Jorge; Apolaya-Segura, Moisés; Pisfil-Farroñay, Yhojar (Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, 2019-03-14)
      Acceso abierto
      En el Editorial mencionan los criterios de autoría para los artículos publicados en la revista, pero nos preguntamos si esos criterios son cumplidos por los asesores de tesis. En el Perú, según la Superintendencia Nacional ...
    • Manifestaciones clínicas de la infección y diversas pruebas utilizadas para el diagnóstico de la infección por el virus Chikungunya 

      Victoria, Pedro; Carina, Ricardo; Carlos, Lugo (Facultad de Medicina, Universidad Central de Venezuela, 2019-04-01)
      Acceso abierto
      Las infecciones virales emergentes se han convertido en un problema grave en los últimos años. Aparición o reaparición de casos graves.Las fiebres hemorrágicas arbovirales causadas por virus ...
    • Bortezomib plus EPOCH is effective as frontline treatment in patients with plasmablastic lymphoma 

      Castillo, Jorge J.; Guerrero‐Garcia, Thomas; Baldini, Francesco; Tchernonog, Emmanuelle; Cartron, Guillaume; Ninkovic, Slavisa; Cwynarski, Kate; Dierickx, Daan; Tousseyn, Thomas; Lansigan, Frederick; Linnik, Yevgeny; Mogollon, Renzo; Navarro, Jose-Tomás; Olszewski, Adam J.; Reagan, John L.; Fedele, Pasquale; Gilbertson, Michael; Grigoriadis, George; Bibas, Michele (John Wiley & Sons Ltd, 2019-02-03)
      Acceso abierto
      Plasmablastic lymphoma (PBL) is a rare and aggressive CD20‐negative lymphoma associated with poor outcomes. Multiple studies have shown median survival times of 12–18 months (Castillo et al, 2012; Schommers et al, 2013; ...
    • The neutrophil‐lymphocyte ratio is prognostic in patients with early stage aggressive peripheral T cell lymphoma 

      Beltran, Brady E.; Castro, Denisse; De la Cruz-Vargas, Jhony A.; Cotrina, Esther; Gallo, Aly; Sotomayor, Eduardo M.; Castillo, Jorge J. (John Wiley & Sons Ltd, 2019-02-03)
      Acceso abierto
      Peripheral T cell lymphoma (PTCL) is rare in the United States and Europe, accounting for about 10% of all lymphoma cases. In Latin America, PTCL accounts for about 15–20% of all lymphoma cases (Laurini et al, 2012). ...
    • Diagnóstico de Bartonella bacilliformis con frotis de sangre periférica: utilidad en países con bajos recursos. 

      Silva-Díaz, Heber; Iglesias-Osores, Sebastian A.; Failoc-Rojas, Virgilio E. (Sociedad Chilena de Infectología, 2019-02)
      Acceso abierto
      "La bartonelosis (también llamada enfermedad de Carrión o verruga peruana) es una enfermedad reemergente tropical causada por Bartonella bacilliformis. Actualmente, se expande a nuevas áreas y regiones del Perú, debido a ...
    • Rising rural body-mass index is the main driver of the global obesity epidemic in adults. 

      Bixby, Honor; Bentham, James; Zhou, Bin; Di Cesare, Mariachiara; Paciorek, Christopher J.; Bennett, James E.; Taddei, Cristina; Stevens, Gretchen A.; Rodriguez-Martinez, Andrea; Carrillo-Larco, Rodrigo M; Khang, Young-Ho; Soric, Maroje; Gregg, Edward W; Miranda, J. Jaime; Bhutta, Zulfiqar A.; Savin, Stefan; Sophiea, Marisa K.; Iurilli, Maria L. C.; Solomon, Bethlehem D.; Cowan, Melanie J.; Riley, Leanne M.; Danaei, Goodarz; Bovet, Pascal; Chirita-Emandi, Adela; Hambleton, Ian R.; Hayes, Alison J.; Ikeda, Nayu; Kengne, Andre P.; Laxmaiah, Avula; Li, Yanping; McGarvey, Stephen T.; Mostafa, Aya; Neovius, Martin; Starc, Gregor; Zainuddin, Ahmad A.; NCD Risk Factor Collaboration (NCD-RisC)* (Springer Nature Limited, 2019-05-08)
      Acceso abierto
      Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities1,2. This has led to a widely reported view that urbanization is one of the most ...
    • Olanzapina para el tratamiento de la psicosis en la enfermedad de Huntington: informe de un caso 

      Huarcaya-Victoria, Jeff; Plasencia-Yasuda, Ray; Nique-Rivas, Manuel; Suárez-Agreda, Karla (Actas Españolas de Psiquiatría, 2019-09)
      Acceso abierto
      El presente artículo presenta el primer caso peruano de un tratamiento satisfactorio con olanzapina en el contexto de una psicosis secundaria a EH, siendo una importante alternativa en países en los cuales no se cuente con ...
    • Cholesterol-lowering treatment in chronic kidney disease: multistage pairwise and network meta-analyses 

      Herrera-Gómez, Francisco; Chimeno, M. Montserrat; Martín-García, Débora; Lizaraso-Soto, Frank; Maurtua-Briseno-Meiggs, Álvaro; Grande-Villoria, Jesús; Bustamante-Munguira, Juan; Alamartine, Eric; Vilardell, Miquel; Ochoa-Sangrador, Carlos; Álvarez, F. Javier (Springer Nature, 2019)
      Acceso abierto
      Pairwise and network meta-analyses on the relationship between the efficacy of the use of statins with or without ezetimibe and reductions in low-density lipoprotein cholesterol (LDLc) and C-reactive protein (CRP) in ...
    • From colorectal cancer pattern to the characterization of individuals at risk: picture for genetic research in Latin America 

      Vaccaro, Carlos Alberto; López-Kostner, Francisco; Della Valle, Adriana; Palmero, Edenir Inez; Rossi, Benedito Mauro; Antelo, Marina; Solano, Angela; Carraro, Dirce Maria; Forones, Nora Manoukian; Bohorquez, Mabel; Lino-Silva, Leonardo S.; Buleje, Jose; Spirandelli, Florencia; Abe-Sandes, Kiyoko; Nascimento, Ivana; Sullcahuaman, Yasser; Sarroca, Carlos; Gonzalez, Maria Laura; Herrando, Alberto Ignacio; Alvarez, Karin; Neffa, Florencia; Galvao, Henrique Camposreis; Esperon, Patricia; Golubicki, Mariano; Cisterna, Daniel; Cardoso, Florencia C.; Torrezan, Giovana Tardin; Aguiar Junior, Samuel; Pimenta, Celia Aparecida Marques; da Cruz Formiga, Maria Nirvana; Santos, Erika; Sa, Caroline U.; Oliveira, Edite P.; Fujita, Ricardo; Spirandelli, Enrique; Jimenez, Geiner; Guindalini, Rodrigo Santa Cruz; de Azevedo, Renata Gondim Meira Velame; Bueno, Larissa Souza Mario; Nogueira, Sonia Tereza dos Santos; Torres Loarte, Mariela; Padron, Jorge; Castro-Mujica, Maria del Carmen; Sanchez del Monte, Julio; Caballero, Carmelo; Muñeton Peña, Carlos Mario; Pinto, Joseph; Barletta-Carrillo, Claudia; Gutiérrez Angulo, Melva; Piñero, Tamara; Montenegro Beltran, Paola; Ashton-Prolla, Patricia; Rodriguez, Yenni; Quispe, Richard; Rossi, Norma Teresa; Martin, Claudia; Chialina, Sergio; Kalfayan, Pablo German; Bazo-Alvarez, Juan Carlos; Recalde Cañete, Alcides; Dominguez-Barrera, Constantino; Nuñez, Lina; Da Silva, Sabrina Daniela; Balavarca, Yesilda; Wernhoff, Patrik; Plazzer, John-Paul; Moller, Pal; Hovig, Eivind; Dominguez-Valentin, Mev (John Wiley & Sons Ltd, 2019)
      Acceso abierto
      Colorectal cancer (CRC) is one of the most common cancers in Latin America and the Caribbean, with the highest rates reported for Uruguay, Brazil and Argentina. We provide a global snapshot of the CRC patterns, how screening ...
    • The current genomic landscape of western south america: andes, amazonia, and pacific coast. 

      Sandoval, José R.; Acosta, Oscar; Zurita, Camilo; Aguilar-Campos, Abraham; Tito-Álvarez, Ana M.; Serrano-Osuna, Ricardo; Gray, Russell D.; Mafessoni, Fabrizio; Heggarty, Paul; Shimizu, Kentaro K.; Fujita, Ricardo; Stoneking, Mark; Pugach, Irina; Fehren-Schmitz, Lars (Society for Molecular Biology and Evolution, 2019-12)
      Acceso abierto
      Studies of Native South American genetic diversity have helped to shed light on the peopling and differentiation of the continent, but available data are sparse for the major ecogeographic domains. These include the Pacific ...
    • First catheter ablations in the Ministry of Health system of Peru: report of the initial experience. 

      Montañez-Valverde, Raúl A.; More, Luis Alberto; Mendoza-Novoa, Pablo (Elsevier B.V., 2019)
      Acceso abierto
      BACKGROUND: In 2015, the Ministry of Health (MINSA) of Peru inaugurated the first national center for electrophysiology studies in a public tertiary referral hospital with the purpose to provide healthcare access to the ...
    • Ansiedad y características en expositores de un concurso científico de estudiantes de medicina peruanos 2019. 

      Romaní-Ojeda, Luccio; Gómez-Rojas, Elice; Vilchez-Cornejo, Jennifer (Sociedad Médica de Santiago, 2019)
      Acceso abierto
      Los estudiantes de medicina que inician tempranamente en la investigación suelen ser muy productivos en el ámbito clínico, científico y de forma particular en salud pública. La investigación y la exposición de los resultados ...
    • Novel and known MYOC exon 3 mutations in an admixed Peruvian primary open-angle glaucoma population 

      Mendoza Reinoso, Veronica; Patil, Teja S.; Guevara Fujita, María Luisa; Fernández, Silvia; Vargas, Enrique; Castillo Herrera, Wilder; Perez Grossmann, Rodolfo; Lizaraso Caparó, Frank; Richards, Julia E.; Fujita, Ricardo (Molecular Vision, 2012)
      Acceso abierto
      Purpose: The aim of this study was to characterize a representative sample of the Peruvian population suffering openangle glaucoma (OAG) with respect to the myocilin gene (MYOC) mutations, glaucoma phenotype, and ancestry ...
    • Mannose-binding lectin and its genetic variants 

      Garred, Peter; Larsen, F.; Seyfarth, J.; Fujita, Ricardo; Madsen, Hans O. (Genes and Immunity, 2006-06-05)
      Acceso abierto
      Mannose-binding lectin (MBL) is a collagen-like serum protein that mediates activation of the complement system and is of importance for host defence. Common variant alleles situated both in the promoter and structural ...
    • Informal Caregiver Burden in Middle-income Countries: Results from Memory Centers in Lima – Peru 

      Custodio, Nilton; Lira, David; Herrera Perez, Eder; Nuñez del Prado, Liza; Parodi García, José Francisco; Guevara Silva, Erik; Castro Suarez, Sheila; Mar, Marcela; Montesinos, Rosa; Cortijo, Patricia (Dementia & Neuropsycholia, 2014-12)
      Acceso abierto
      Objective: The aim of this study was to evaluate caregiver burden based on Zarit Burden Interview (ZBI) and depression in caregivers on the Beck Depression Inventory-II (BDI-II). Methods: Literate individuals, 18 years ...
    • Prevalence and Factors Associated with Frailty Among Peruvian Older Adults 

      Runzer Colmenares, Fernando M.; Samper Ternent, Rafael; Al Snih, Soham; Ottenbacher, Kenneth J.; Parodi García, José Francisco; Wong, Rebeca (Archives of Gerontology and Geriatrics, 2014-01-01)
      Acceso abierto
      The objective of this study is to examine the prevalence and factors associated with frailty in Peruvian Navy Veteran's older adults and family members. A total of 311 non-institutionalized men and women aged 60 years ...
    • The Memory Alteration Test Discriminates between Cognitively Healthy Status, Mild Cognitive Impairment and Alzheimer’s Disease 

      Custodio, Nilton; Lira, David; Herrera Perez, Eder; Nuñez del Prado, Liza; Parodi García, José Francisco; Guevara Silva, Erik; Castro Suarez, Sheila; Montesinos, Rosa; Cortijo, Patricia (Dementia and Geriatric Cognitive Disorder Extra, 2014)
      Acceso abierto
      Background/Aims: Dementia is a worldwide public health problem and there are several diagnostic tools for its assessment. The aim of this study was to evaluate the performance of the Memory Alteration Test (M @ T) to ...
    • Genetic Variations in the TP53 Pathway in Native Americans Strongly Suggest Adaptation to the High Altitudes of the Andes 

      Jacovas, Vanessa Cristina; Luiz Rovaris, Diego; Peréz, Orlando; Azevedo, Soledad de; Souza Macedo, Gabriel; Sandoval Sandoval, José Raul; Salazar Granara, Alberto; Villena, Mercedes; Dugoujon, Jean-Michel; Bisso-Machado, Rafael; Petzl- Erler, Maria Luiza; Mauro Salzano, Francisco; Ashton-Prolla, Patricia; Ramallo, Virginia; Cátira Bortolini, Maria (PLOS ONE, 2015-09)
      Acceso abierto
      The diversity of the five single nucleotide polymorphisms located in genes of the TP53 pathway (TP53, rs1042522; MDM2, rs2279744; MDM4, rs1563828; USP7, rs1529916; and LIF, rs929271) were studied in a total of 282 ...