Factores de riesgo asociados a progresión bioquímica postprostatectomía radical Hospital Nacional Luis Nicasio Saenz 2009-2017

Abstract

Objective: To determine the risk factors associated with biochemical progression after radical prostatectomy. National Hospital Luis Nicasio Sáenz 2009-2017. Methodology: Analytical, retrospective, cases and controls. The population consisted of 54 patients with prostate cancer operated on by prostatectomy who met the selection criteria, which were distributed in a case group and a control group; a patient with PSA> 0.2 ng / ml after radical prostatectomy was defined as a case. The Chi square test and odds ratio were used. Results: The average age of patients with and without biochemical progression after prostatectomy was 63.4±4.9 and 63.4±6 years, respectively, without significant differences (p = 0,982), the distribution by age groups showed that the majority is between 60 to 69 years. The risk factors for biochemical progression were: Gleason score> 7 (p = 0.028, OR = 3.55; 95% CI: 1.12-11.28), surgical edge compromised (p = 0,007, OR = 5.07; 95% CI: 1.54-16.64), compromised seminal vesicles (p=0.013; OR=6.154; IC95%: 1.404-26.977) and tumor size greater than 20 mm (p = 0.027, OR = 4.200, 95% CI: 1,161-15.189). Conclusion: The risk factors for biochemical progression in patients with prostate cancer are Gleason> 7, compromised surgical border, seminal vesicles compromised and tumor size greater than 20 mm.