Factores de riesgo de la adherencia del targa en pacientes VIH/Sida. Hospital Nacional Daniel Alcides Carrión, años 2012 - 2013

Abstract

Objective: The main objective of the study was to determine the risk factors for the lack of the adherence of the treatment antiretroviral therapy (HAART) in HIV / AIDS patients treated at the Daniel Alcides Carrión National Hospital (HNDAC) in the city of Callao, In the years 2012 and 2013. Materials and methods: The study design and type is observational, retrospective. The study group is made up of patients diagnosed with HIV / AIDS who received highly active antiretroviral therapy (HAART) in the years 2012 and 2013. For the collection of data, a registry was created for this purpose. Which filled out the required data with the medical records of each patient. After completing the field work, the data were processed in the SPSS version 25 statistical package to perform the corresponding statistical analysis. Conclusions: 120 patients were included, of which 43 (35.8%) were cases of nonadherence to treatment. 63 (52.5%) were men and 57 (47.5%) women. The followed schemes were AZT + 3TC + EFV 57 (47.5%), followed by the AZT + 3TC + NVP 40 scheme (33.3%). The main reasons given for the lack of adherence to HAART were forgetfulness of taking medication 16 (72.7%), followed by hourly difficulty 10 (76.9%), and the belief of negative effects 5 (71.4%). The factors associated (<0.05) with this lack of adherence were mainly weight loss (n = 35: 63.6%), followed by age younger than 35 years (n = 32: 57.1%), the level of viral load greater than 400 copies / ml (n = 30, 54.6%) and finally the female sex (n = 30: 52.6%).