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dc.contributor.authorde Paz, Nicole C.
dc.contributor.authorSanchez, Sixto E.
dc.contributor.authorHuaman, Luis E.
dc.contributor.authorDiez Chang, Guillermo
dc.contributor.authorPacora, Percy N.
dc.contributor.authorGarcia, Pedro J.
dc.contributor.authorAnanth, Cande V.
dc.contributor.authorQiu, Chungfang
dc.contributor.authorWilliams, Michelle A.
dc.date.accessioned2020-07-17T15:53:39Z
dc.date.available2020-07-17T15:53:39Z
dc.date.issued2011-04
dc.identifier.citationde Paz NC., Sanchez SE., Huaman LE., Chang GD., Pacora PN., Garcia PJ., et al. Risk of placental abruption in relation to maternal depressive, anxiety and stress symptoms. J Affect Disord. 2011; 130(1-2): 280-284.es_PE
dc.identifier.issn0165-0327
dc.identifier.urihttps://hdl.handle.net/20.500.12727/6357
dc.description.abstractBackground Little is known about the influence of psychiatric factors on the etiology of placental abruption (PA), an obstetrical condition that complicates 1–2% of pregnancies. We examined the risk of PA in relation to maternal psychiatric symptoms during pregnancy. Methods This case–control study included 373 PA cases and 368 controls delivered at five medical centers in Lima, Peru. Depressive, anxiety and stress symptoms were assessed using the Patient Health Questionnaire (PHQ-9) and the Depression Anxiety Stress Scales (DASS-21). Multivariable logistic regression models were fit to calculate odds ratios (aOR) and 95% confidence intervals (CI) adjusted for confounders. Results Depressive symptoms of increasing severity (using the DASS depression subscale) was associated with PA (p for trend = 0.02). Compared with women with no depressive symptoms, the aOR (95%CI) for PA associated with each level of severity of depression symptoms based on the DASS assessment were as follows: mild 1.84 (0.91–3.74); moderate 1.25 (0.67–2.33); and severe 4.68 (0.98–22.4). The corresponding ORs for mild, moderate, and moderately severe depressive symptoms based on the PHQ assessment were 1.10 (0.79–1.54), 3.31 (1.45–7.57), and 5.01 (1.06–23.6), respectively. A positive gradient was observed for the odds of PA with severity of anxiety (p for trend = 0.002) and stress symptoms (p for trend = 0.002). Limitations These cross-sectionally collected data may be subject to recall bias. Conclusions Maternal psychiatric disorders may be associated with an increased occurrence of AP. Larger studies that allow for more precise evaluations of maternal psychiatric health in relation to PA risk are warranted.es_PE
dc.format.extentpp. 280-284es_PE
dc.language.isoenges_PE
dc.publisherElsevieres_PE
dc.relation.ispartofseriesJournal of Affective Disorders;vol. 130, no. 1-2
dc.relation.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994998/es_PE
dc.relation.urihttps://doi.org/10.1016/j.jad.2010.07.024
dc.rightsinfo:eu-repo/semantics/openAccesses_PE
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/es_PE
dc.sourceRepositorio Académico USMPes_PE
dc.sourceUniversidad San Martín de Porres - USMPes_PE
dc.subjectDesprendimiento prematuro de la placentaes_PE
dc.subjectEpidemiologíaes_PE
dc.subjectEmbarazoes_PE
dc.subjectDepresiónes_PE
dc.subjectAnsiedades_PE
dc.subjectFactores de riesgoes_PE
dc.titleRisk of placental abruption in relation to maternal depressive, anxiety and stress symptomses_PE
dc.typeinfo:eu-repo/semantics/articlees_PE
thesis.degree.nameMedicina Humana
thesis.degree.grantorUniversidad de San Martín de Porres. Facultad de Medicina Humana
thesis.degree.disciplineMedicina


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