• Genetic Variations in the TP53 Pathway in Native Americans Strongly Suggest Adaptation to the High Altitudes of the Andes 

      Jacovas, Vanessa Cristina; Luiz Rovaris, Diego; Peréz, Orlando; Azevedo, Soledad de; Souza Macedo, Gabriel; Sandoval Sandoval, José Raul; Salazar Granara, Alberto; Villena, Mercedes; Dugoujon, Jean-Michel; Bisso-Machado, Rafael; Petzl- Erler, Maria Luiza; Mauro Salzano, Francisco; Ashton-Prolla, Patricia; Ramallo, Virginia; Cátira Bortolini, Maria (PLOS ONE, 2015-09)
      Acceso abierto
      The diversity of the five single nucleotide polymorphisms located in genes of the TP53 pathway (TP53, rs1042522; MDM2, rs2279744; MDM4, rs1563828; USP7, rs1529916; and LIF, rs929271) were studied in a total of 282 ...
    • Y chromosome sequences reveal a short beringian standstill, rapid expansion, and early population structure of native american founders 

      Pinotti, Thomaz; Bergström, Anders; Geppert, Maria; Bawn, Matt; Ohasi, Dominique; Shi, Wentao; Lacerda, Daniela R.; Solli, Arne; Norstedt, Jakob; Reed, Kate; Dawtry, Kim; González-Andrade, Fabricio; Paz-y-Miño, Cesar; Revollo, Susana; Cuellar, Cinthia; Jota, Marilza S.; Santos Jr., José E.; Ayub, Qasim; Kivisild, Toomas; Sandoval, José R.; Fujita, Ricardo; Xue, Yali; Roewer, Lutz; Santos, Fabrício R.; Tyler-Smith, Chris (Elsevier Ltd., 2018-12-20)
      Acceso abierto
      The Americas were the last inhabitable continents to be occupied by humans, with a growing multidisciplinary consensus for entry 15–25 thousand years ago (kya) from northeast Asia via the former Beringia land bridge [1, ...