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Risk of placental abruption in relation to maternal depressive, anxiety and stress symptoms
(Elsevier, 2011-04)
Acceso abierto
Background
Little is known about the influence of psychiatric factors on the etiology of placental abruption (PA), an obstetrical condition that complicates 1–2% of pregnancies. We examined the risk of PA in relation to ...
Genetic variations and risk of placental abruption: a genome-wide association study and meta-analysis of genome-wide association studies
(Elsevier Ltd., 2018-04-16)
Acceso abierto
Introduction
Accumulating epidemiological evidence points to strong genetic susceptibility to placental abruption (PA). However, characterization of genes associated with PA remains incomplete. We conducted a genome-wide ...
Circadian clock-related genetic risk scores and risk of placental abruption
(Elsevier Ltd., 2015-12)
Acceso abierto
Introduction
The circadian clock plays an important role in several aspects of female reproductive biology. Evidence linking circadian clock-related genes to pregnancy outcomes has been inconsistent. We sought to examine ...
Genome-wide and candidate gene association studies of placental abruption
(e-Century Publishing, 2013-09-12)
Acceso abierto
Placental abruption (PA), a pregnancy-related vascular disorder, is a leading cause of maternal and perinatal morbidity and mortality. The success of identifying genetic susceptibility loci for PA, a multi-factorial heritable ...
Placental genome and maternal-placental genetic interactions: a genome-wide and candidate gene association study of placental abruption
(Plos, 2014-12-30)
Acceso abierto
While available evidence supports the role of genetics in the pathogenesis of placental abruption (PA), PA-related placental genome variations and maternal-placental genetic interactions have not been investigated. Maternal ...
Maternal sleep duration and complaints of vital exhaustion during pregnancy is associated with placental abruption
(Informa Healthcare, 2015-02)
Acceso abierto
OBJECTIVE
Sleep disorders are associated with cardiovascular complications and preterm delivery (PTD). Insufficient sleep results in metabolic alterations and increased inflammation, both known to contribute to placental ...
A genome-wide association study of variations in maternal cardiometabolic genes and risk of placental abruption
(e-Century Publishing, 2012-11-05)
Acceso abierto
Accumulating evidence suggests that placental abruption has a complex multifactorial pathogenesis that involves cardiovascular risk and metabolic dysfunction. However, comprehensive assessment of variations in genes involved ...
Maternal blood mitochondrial DNA copy number and placental abruption risk: results from a preliminary study
(e-Century Publishing, 2013-06-25)
Acceso abierto
Oxidative stress and impaired placental function – pathways implicated in the pathogenesis of placental abruption – have their origins extending to mitochondrial dysfunction. To the best of our knowledge, there are no ...